Epigenetic regulation of axon and dendrite growth
نویسندگان
چکیده
منابع مشابه
Epigenetic regulation of axon and dendrite growth
Neuroregenerative therapies for central nervous system (CNS) injury, neurodegenerative disease, or stroke require axons of damaged neurons to grow and re-innervate their targets. However, mature mammalian CNS neurons do not regenerate their axons, limiting recovery in these diseases. Although neurons' intrinsic capacity for axon growth may depend in part on the panoply of expressed transcriptio...
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Guidance factors act on the tip of a growing axon to direct it to its target. What role these molecules play, however, in the control of the dendrites that extend from that axon's cell body is poorly understood. Slits, through their Robo receptors, guide many types of axons, including those of retinal ganglion cells (RGCs). Here we assess and contrast the role of Slit/Robo signalling in the gro...
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ژورنال
عنوان ژورنال: Frontiers in Molecular Neuroscience
سال: 2012
ISSN: 1662-5099
DOI: 10.3389/fnmol.2012.00024